T\u00eb nderuar qytetar\u00eb dhe bashk\u00ebpun\u00ebtor\u00eb,
\nShfaqja e variantit t\u00eb ri t\u00eb Botswana SARS CoV, lloji Omicron m\u00eb 24 n\u00ebntor 2021, \u00ebsht\u00eb p\u00ebrshkruar si lloji m\u00eb i friksh\u00ebm i virusit i njohur nga ekspert\u00ebt deri m\u00eb tani dhe \u00ebsht\u00eb nj\u00eb fenomen intrigues p\u00ebr k\u00ebrkime, ve\u00e7an\u00ebrisht nga biolog\u00ebt molekular\u00eb, virolog\u00ebt dhe nga pjesa tjet\u00ebr e stafit profesional.<\/p>\n
Lloji i ri i sistemuar si VOC B.1.1.529 ka n\u00eb gjenomin e tij t\u00eb gjitha \"mutacionet shqet\u00ebsuese\" tashm\u00eb t\u00eb pranishme n\u00eb llojet e tjera t\u00eb COVID, si dhe mutacione shtes\u00eb q\u00eb kontribuojn\u00eb n\u00eb infektivitetin dhe rezistenc\u00ebn ndaj vaksinave aktualisht t\u00eb disponueshme. \u201cSuper lloji\u201d i ri ka p\u00ebrvet\u00ebsuar t\u00eb gjitha mutacionet nga lloji Delta, i cili u jep shkenc\u00ebtar\u00ebve t\u00eb drejt\u00ebn t\u00eb presin transmetim dhe dominim m\u00eb intensiv n\u00eb procesin infektiv n\u00eb nivelin e popullsis\u00eb njer\u00ebzore, krahasuar me llojet e shfaqura m\u00eb par\u00eb.
\nOmicron mbart gjithashtu ndryshime gjenetikisht specifike n\u00eb llojin Beta, t\u00eb cilat jan\u00eb p\u00ebrgjegj\u00ebse p\u00ebr rezistimin e imunitetit t\u00eb fituar artificialisht me vaksinat e disponueshme, si dhe karakteristik\u00ebn e mutacionit t\u00eb llojit Alfa. N\u00eb total, lloji i ri mbart m\u00eb shum\u00eb se 50 mutacione n\u00eb t\u00eb gjith\u00eb gjenom\u00ebn virale (positive sense ssRNA), nga t\u00eb cilat vet\u00ebm 32 mutacione ndodhen n\u00eb gjenin q\u00eb kodon protein\u00ebn Spike. P\u00ebr shkak t\u00eb numrit t\u00eb madh t\u00eb mutacioneve n\u00eb gjenin S, produkti i tij funksional proteinik - proteina Spike fiton nj\u00eb konformacion tredimensional krejt\u00ebsisht t\u00eb ndrysh\u00ebm dhe b\u00ebhet i panjohur p\u00ebr antitrupat e induktuar artificialisht n\u00eb nj\u00eb organiz\u00ebm t\u00eb caktuar, pra n\u00ebn veprimin e nj\u00eb vaksine, e cila u krijua posa\u00e7\u00ebrisht p\u00ebr struktur\u00ebn fillestare 3D t\u00eb protein\u00ebs S. Tre z\u00ebvend\u00ebsimet e aminoacideve H665Y, N679K dhe P681H lejojn\u00eb internizimin m\u00eb t\u00eb leht\u00eb t\u00eb virusit n\u00eb qeliz\u00ebn prit\u00ebse, nd\u00ebrsa z\u00ebvend\u00ebsimet R203K dhe G204R mbahen n\u00eb proteom\u00ebn Omicron dhe jan\u00eb t\u00eb pranishme n\u00eb t\u00eb gjitha llojet q\u00eb kan\u00eb ekzistuar m\u00eb par\u00eb t\u00eb p\u00ebrcaktuara nga OBSH si nj\u00eb shqet\u00ebsim (VOC \u2013 Variant of Concern).
\nZinxhiri laboratorik i laborator\u00ebve t\u00eb specializuar diagnostikues BIOTEK n\u00eb Shkup dhe p\u00ebrmes bashk\u00ebpunimit q\u00eb ka n\u00eb nivel komb\u00ebtar dhe nd\u00ebrkomb\u00ebtar me qendrat e tjera diagnostikuese t\u00eb p\u00ebrfshira n\u00eb depistimin gjat\u00eb pandemis\u00eb COVID, monitoron \u00e7do incident dhe ofron zgjidhje t\u00eb plot\u00eb p\u00ebr diagnostifikimin e llojit t\u00eb ri OMICRON p\u00ebrmes metod\u00ebs RT-PCR n\u00eb nivel gjenetik. Konkretisht, krahasuar dhe analizuar n\u00eb baz\u00eb t\u00eb t\u00eb dh\u00ebnave t\u00eb disponueshme bioinformatike mbi mutacionet n\u00eb llojin B.1.1.529 t\u00eb virusit korona, u p\u00ebrcaktua se mutacionet e shtjelluara m\u00eb sip\u00ebr n\u00eb gjenom\u00ebn e llojit t\u00eb ri nuk ndikojn\u00eb n\u00eb vetit\u00eb diagnostike t\u00eb SARS CoV- 2 \/ Testi SARS CoV Multiplex Real Time PCR, prodhuar nga DNA Technology, Rusi.<\/p>\n
Gjegj\u00ebsisht, konstruksioni i panelit multipleks t\u00eb testit \u00ebsht\u00eb i destinuar pik\u00ebrisht p\u00ebr zbulimin dhe diferencimin e 3 gjeneve, 2 prej t\u00eb cilave jan\u00eb shum\u00eb specifike dhe t\u00eb ndryshueshme p\u00ebr SARS CoV-2 dhe 1 gjen karakteristik p\u00ebr t\u00eb gjith\u00eb familjen e Coronaviridae q\u00eb p\u00ebrfshin t\u00eb gjith\u00eb mutant\u00ebt dhe llojet e sapoformuar.<\/p>","protected":false},"excerpt":{"rendered":"
Dear citizens and associates, The appearance of the new Botswana SARS CoV variant, Omicron strain on November 24, 2021, has been described as the most feared strain of the virus known to experts so far and is an intriguing phenomenon for research, especially by molecular biologists, virologists and other professional staff. The new strain systematized […]<\/p>","protected":false},"author":4,"featured_media":3432,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[88,1,75,89],"tags":[130,126,128,129,104,127],"class_list":["post-3431","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogu","category-news","category-one-news","category-one-news_sq","tag-biteok-laboratory","tag-covid-19","tag-delta","tag-omicron","tag-one-hospital","tag-spike-protein"],"acf":[],"yoast_head":"\n